VIRTUAL ROOM 1

Symposium 1.1 Epitranscriptomics and RNA editing
(Chair: Diana Guallar)

09:30 h.

• Michael Jantsch, Center of Anatomy and Cell Biology, Vienna, Austria

“From RNA-editing to smooth muscle contraction: Biomedical implications of RNA modification”

10:00 h.

• Francesca Aguiló, Wallenberg Center for Molecular Medicine, Umeå, Sweden

“The epitranscriptome: a new era for cancer research”

10:30 h.

• Diana Guallar, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Santiago de Compostela

“Diverse functions of RNA modifications in pluripotency and somatic cell reprogramming”

VIRTUAL ROOM 2

Symposium 1.2 The hidden world of small ORF-encoded microproteins

(Chair: María Abad, VHIO, Barcelona)

9:30 h.

• Juan Pablo Couso, Centro Andaluz de Biología del Desarrollo CSIC-UPO, Sevilla.

 “Small ORFs: from sequence to function”

10:00 h.

• Mar Albà. IMIM, Barcelona.

“The birth of new proteins from scratch”

10:30 h.

• Maria Abad, Vall d’Hebron Institute of Oncology (VHIO), Barcelona.

 “The microproteome as a source of novel cancer players”

VIRTUAL ROOM 3

Symposium 1.3 Novel approaches in structural biology.
(Chair: Damien Devos / Oriol Gallego)

09:30 h.

• Maya Topf, Birkbeck, University of London. United Kingdom.

“Modeling protein structures in (cryo-)EM maps”

10:00 h.

• Damien Devos, Centro Andaluz de Biología del Desarrollo CSIC-UPO, Seville

“In vivo architecture of the Exocyst and beyond”

10:30 h.

• Ben Lehner, Centre for Genomic Regulation (CRG), ICREA, Barcelona

“Solving protein structures using deep mutagenesis”

VIRTUAL ROOM 1

Symposium 2.1 Cellular reprogramming beyond pluripotency
(Chair: Manuel Collado)

09:30 h.

• Manuel Collado, Health Research Institute of Santiago de Compostela, IDIS, Santiago de Compostela

“Cellular reprogramming of cancer”

10:00 h.

• Alejandro Ocampo, University of Lausanne, Lausanne, Switzerland

“Novel epigenetic approaches for the treatment of aging and disease”

10:30 h.

• Han Li, Pasteur Institute, Paris, France

“Modulating cellular plasticity in tissue regeneration”

VIRTUAL ROOM 2

Symposium 2.2 In memoriam: José Luis Gómez-Skarmeta
(Chair: Marc Marti-Renom)

09:30 h.

• Lluís Montoliu, Centro Nacional de Biotecnología, Madrid

10:00 h.

• Marc A. Marti-Renom, CNAG-CRG, Barcelona

“3DGWAS, genome-wide association studies informed by genome structure”

10:30 h.

• Jorge Ferrer, CRG & CIBERDEM, Barcelona

“3D genomics and diabetes mellitus”

VIRTUAL ROOM 3

Symposium 2.3 Biomolecular condensation
(Chair: Xavier Salvatella)

09:30 h.

• Xavier Salvatella, IRB Barcelona and ICREA Barcelona

“Biomolecular condensation as a mechanism to regulate gene expression”

10:00 h.

• Benedetta Bolognesi, IBEC, Barcelona

“Understanding Phase Transitions by Deep Mutagenesis”

10:30 h.

• Avinash Patel, Max Planck Institute for Molecular and Cellular Biology, Germany

“Biomolecular condensates for drug discovery in ALS”

VIRTUAL ROOM 1

Symposium 3.1 Chromatin plasticity and multifunctionality
(Chair: Eulàlia de Nadal)

09:30 h.

• Eulàlia de Nadal, IRB Barcelona & Pompeu Fabra University (UPF), Barcelona

“Regulation of gene expression by Stress-Activated Protein Kinases”

10:00 h.

• Biola Javierre, Josep Carreras Leukaemia Research Institute (IJC), Barcelona

 “Spatial-temporal genome architecture: understanding the contribution of non-coding variants to disease development”

10:30 h.

• Sara Sdelci, Centre for Genomic Regulation (CRG), Barcelona

 “Dissecting the ChroMetOme: an unexpected metabolism provides novel cancer vulnerabilities”

VIRTUAL ROOM 2

Symposium 3.2 The mTOR pathway in health and disease
(Chair: Alejo Efeyan)

09:30 am.

• Alejo Efeyan, Spanish National Cancer Research Center (CNIO), Madrid

“The nutrients-mTOR axis in cancer and aging”

10:00 am.

• Mario Pende, Institut Necker Enfants Malades, Inserm, Paris Sorbonne University, France

“Pathological targets of mTOR in cyst formation and seizures”

10:30 am.

• Andrea Ballabio, Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

“A substrate-specific mTORC1 pathway mediates selective control of cell metabolism”

VIRTUAL ROOM 3

Symposium 3.3 Structural mechanisms of RNA/DNA transactions
(Chair: Rafael Fernández-Leiro)

09:30 am.

• Israel S. Fernández, Columbia University, New York, USA

“DNA targeting by a transposon encoded CRISPR/CAS system”

10: 00 am.

• Nuria Verdaguer, Molecular Biology Institute of Barcelona-CSIC, Barcelona

“Structural Insights into the dynamics and opening of vault particles”

10:30 am.

• Rafael Fernández Leiro, Spanish National Cancer Research Centre-CNIO, Madrid

“Capturing the elusive DNA Mismatch Repair machinery by cryo-EM”